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Related Experiment Video

Updated: May 3, 2026

A Morphometric and Cellular Analysis Method for the Murine Mandibular Condyle
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Improving TMJ Diagnosis: A Deep Learning Approach for Detecting Mandibular Condyle Bone Changes.

Kader Azlağ Pekince1, Adem Pekince1, Buse Yaren Kazangirler2,3

  • 1Department of Oral and Maxillofacial Radiology, Karabuk University, Karabuk 78600, Turkey.

Diagnostics (Basel, Switzerland)
|May 1, 2025
PubMed
Summary

Deep learning accurately detects degenerative bone changes in the mandibular condyle from panoramic radiographs. This artificial intelligence approach aids in diagnosing temporomandibular joint (TMJ) conditions early.

Keywords:
convolutional neural networksdeep learningdegenerative bone changesmandibular condylepanoramic radiographytemporomandibular joint

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Area of Science:

  • Dentistry and Oral Health
  • Medical Imaging
  • Artificial Intelligence in Medicine

Background:

  • Degenerative bone changes in the mandibular condyle are challenging to diagnose using traditional panoramic radiographs.
  • Early detection of these changes is crucial for timely intervention and preventing temporomandibular joint (TMJ) disease progression.

Purpose of the Study:

  • To evaluate the efficacy of deep learning (DL) models for detecting degenerative bone changes in the mandibular condyle.
  • To develop an automated method for identifying conditions like flattening, osteophyte, and erosion on panoramic radiographs.

Main Methods:

  • Utilized a dataset of 3875 condylar images from panoramic radiographs.
  • Employed various deep learning architectures (DenseNets, ResNets, VGGNets, GoogleNets) with transfer learning.
  • Trained and tested models using 70:30 and 80:20 data splits, considering different classification approaches for bone changes.

Main Results:

  • GoogleNet architecture achieved the highest accuracy of 95.23% with an 80:20 split for the normal-flattening-deformation dataset.
  • Convolutional Neural Network (CNN)-based methods demonstrated high success rates in identifying mandibular condyle bone abnormalities.
  • The study confirmed the effectiveness of DL in classifying condylar bone changes.

Conclusions:

  • Deep learning, especially CNNs, shows significant potential for accurate and efficient detection of TMJ-related condylar bone changes from panoramic radiographs.
  • This AI-driven approach can assist clinicians in identifying patients needing further intervention for TMJ disorders.
  • Future research should explore cross-sectional imaging and combined training of condyles to enhance diagnostic accuracy and disease management.