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Updated: May 8, 2026

Preparation of DNA-crosslinked Polyacrylamide Hydrogels
Published on: August 27, 2014
DNA-Based Networks Formed by Coordination Cross-Linking of DNA with Metal-Organic Polyhedra: From Gels to Aerogels to
Laura Hernández-López1,2, Akim Khobotov-Bakishev1,2, Alba Cortés-Martínez1,2
1Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC, and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra 08193, Spain.
Abstract:
Herein, we introduce a supramolecular method to form DNA-based networks by cross-linking DNA with Rh(II)-based metal-organic polyhedra (MOPs), which entails coordination of DNA to the exohedral Rh(II) axial sites of the MOP. The resultant highly connected networks can then be processed into gels, porous aerogels, or hydrogels, exhibiting properties suitable for pollutant removal and drug release.
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