Artificial Intelligence in Biliopancreatic Disorders: Applications in Cross-Sectional Imaging and Endoscopy

This review explores the transformative potential of artificial intelligence (AI) in the diagnosis and management of biliopancreatic disorders. By leveraging cutting-edge techniques, such as deep learning and convolutional neural networks, AI has significantly advanced gastroenterology, particularly in endoscopic procedures, such as colonoscopy; upper endoscopy; and capsule endoscopy. These applications enhance adenoma detection rates and improve lesion characterization and diagnostic accuracy. AI's integration in cross-sectional imaging modalities, such as computed tomography and magnetic resonance imaging, has remarkable potential. Models have demonstrated high accuracy in identifying pancreatic ductal adenocarcinoma; pancreatic cystic lesions; and pancreatic neuroendocrine tumors, aiding in early diagnosis; resectability assessment; and personalized treatment planning. In advanced endoscopic procedures, such as digital single-operator cholangioscopy and endoscopic ultrasound, AI enhances anatomic recognition and improves lesion classification, with a potential for reduction in procedural variability, enabling more consistent diagnostic and therapeutic outcomes. Promising applications in biliopancreatic endoscopy include the detection of biliary stenosis, classification of dysplastic precursor lesions, and assessment of pancreatic abnormalities. This review aims to capture the current state of AI application in biliopancreatic disorders, summarizing the results of early studies and paving the path for future directions.