Quality of life and physical activity in type 1 diabetes
Emma J Cockcroft1, Dillon Chithuranjan2, Parth Narendran3,4
1University of Exeter Medical School, Exeter, EX1 2JP, UK.
Insights
Physical activity interventions show unclear benefits for the quality of life in children with type 1 diabetes (T1D). More research is needed to understand long-term physical and psychological health impacts in this population.
Area of Science:
- Pediatric Endocrinology
- Exercise Science
- Public Health
Background:
- Type 1 Diabetes (T1D) affects numerous children and young people globally.
- Physical activity is recognized for its benefits in diabetes management, including improved glycemic control.
- The impact of physical activity on the quality of life (QoL) for children with T1D remains uncertain due to confounding factors.
Purpose of the Study:
- To systematically review the effects of physical activity interventions on the quality of life in children diagnosed with type 1 diabetes.
Main Methods:
- A systematic review adhering to PRISMA 2009 guidelines was conducted.
- Searches were performed across multiple databases (CINAHL, Embase, Medline, PubMed, PsychINFO) from January 1994 to March 2025.
- Included studies featured interventions in children under 19 with T1D, excluding single sessions, and required a control group; QoL indicators were the primary outcome.
Main Results:
- Out of 3020 assessed records, only three randomized controlled trials (RCTs) published between 2007 and 2020 met the inclusion criteria.
- Significant heterogeneity was observed in study designs, methodologies, and reporting across the included trials.
- The benefits of physical activity on QoL were not consistently demonstrated across the studies.
Conclusions:
- Limited data exists regarding QoL outcomes and standardized measurement tools for children with T1D.
- Further research is essential to elucidate the psychological underpinnings necessary for sustained physical and psychological health improvements in pediatric T1D.
- There is a need for standardized QoL assessment in children with T1D to better evaluate intervention effectiveness.
Introduction:
T1 Diabetes (T1D) is one of the most common chronic diseases in children and young people [1] with almost 34 000 aged 18 years or less living with T1D [2]. Physical activity is promoted as one of a number of management tools for people living with diabetes, being associated with significant health benefits including improved glycaemic control. The benefits of physical activity on quality of life in children with T1D is unclear with confounding effects of disease duration and co-morbidities in studies.
Aim:
To determine the effect of physical activity interventions on quality of life of children with type 1 diabetes.
Methods:
A systematic review was conducted and reported in line with PRISMA 2009 guidance. The CINAHL, Embase, International Pharmaceutical Abstracts, Medline, PubMed and PsychINFO databases were searched for the period January 1994 to March 2025. Papers were included in the present review if they included a study intervention in children under 19 years of age that was more than a single exercise session and had a control group (with or without T1D) as a comparator group. The primary outcome measure was Quality of Life (QoL) indicators.
Results:
We assessed 3020 records, of which three randomised controlled trials (RCT) published between 2007 and 2020 met study inclusion criteria. There was significant heterogeneity in study design, methods and reporting. Benefits of physical activity were not consistently seen across studies.
Conclusion:
There remains limited data on QoL outcomes or even a standardisation for measuring QoL in this cohort as seen by the various validated tools used across studies. There continues to be a need for further work to understand the additional framework (psychological underpinning) to cause longer term impactful changes on both physical and psychological health in children with T1D.
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