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A retrospective chart review study of patients treated in a hospital-based brexanolone program
Zobeida M Diaz1,2, Margaret M Howard3,4, Keyline V Moreno5,6
1Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI, USA. zdiaz@wihri.org.
Purpose:
Postpartum depression (PPD), the most common childbirth complication in the United States, can be treated using brexanolone, an intravenous form of allopregnanolone.
Methods:
This retrospective chart review study evaluated clinical outcomes of 64 postpartum women who received brexanolone infusion for PPD in a real-world setting.
Results:
Treatment was associated with improved depression and anxiety symptoms, and 71% of patients reported significant improvement in their PPD.
Conclusions:
While further research is needed, this study supports brexanolone as an efficacious treatment for PPD.
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