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[Monomeric IgM in lymphoproliferative, autoimmune and infectious diseases in man (author's transl)]
Abstract:
7S-IgM is the first specific antibody during evolution of vertebrates. The detection of monomeric IgM in monoclonal grammopathies, autoimmune and infectious diseases is believed to be an atavistic primary IgM response in cases of elevated humoral immune reactions and disorders of lymphatic tissues.