Recurrent uncomplicated lower urinary tract infections in women

Recurrent uncomplicated lower urinary tract infections (RULUTIs) are common among women without anatomical or physiological abnormalities and affect women of all age groups, races, and ethnicities. Herein, we summarized the sources of epidemiology, etiology, diagnosis, treatment, prophylaxis, and follow-up evaluations in cases of RULUTIs. Patients' medical histories, symptoms, and signs were recorded. The review showed that urinalysis, culture, and sensitivity should be tested before empiric treatment. A first-line therapeutic strategy should be applied based on the results of the urine culture and sensitivity tests. Therefore, estrogen should be used as an ancillary therapy. After the successful treatment of acute infections, intermittent or continuous prophylaxis can be administered. Patients may benefit from follow-up evaluations to avoid recurrent infections. We expect that clinicians will pay more attention to RULUTIs.