Improving Timely Diagnosis of Arterial Ischemic Stroke at a Pediatric Emergency Department

Theodore E Trigylidas1,2, Nichole L McCollum1,2, Kathleen M Brown1,2

  • 1Children's National Hospital, Washington, DC.

Pediatrics
|May 2, 2025
PubMed

Insights

Implementing a stroke alert team significantly reduced diagnosis time for pediatric arterial ischemic stroke (AIS). This protocol improvement ensures faster neuroimaging for children with suspected AIS, improving critical care.

Area of Science:

  • Pediatric Neurology
  • Emergency Medicine
  • Quality Improvement Science

Background:

  • Pediatric arterial ischemic stroke (AIS) is a critical condition demanding rapid diagnosis for effective hyperacute treatment.
  • Timely recognition of AIS in children is essential to mitigate significant morbidity and mortality.

Purpose of the Study:

  • To enhance the prompt diagnosis of pediatric AIS by implementing an interdisciplinary stroke response protocol.
  • To reduce the median door-to-imaging time for pediatric patients presenting with suspected AIS.

Main Methods:

  • A quality improvement initiative utilizing Plan-Do-Study-Act cycles was conducted from November 2019 to June 2023.
  • Interventions included educational programs, a dedicated stroke alert paging system, and optimized stroke order sets.
  • Data from 71 pediatric patients (0-21 years) with suspected AIS undergoing emergency department neuroimaging were analyzed.

Main Results:

  • Median door-to-imaging time for suspected AIS decreased from 128 minutes to 68 minutes post-intervention.
  • For patients with confirmed AIS on neuroimaging, median door-to-imaging time also improved to 68 minutes.
  • Statistical process control charts monitored changes in door-to-imaging times over the study period.

Conclusions:

  • The establishment of stroke alert teams can significantly improve the coordination of care for pediatric AIS.
  • Expedited neuroimaging for children with suspected AIS is achievable through structured stroke response protocols.
  • Interdisciplinary collaboration is key to enhancing the efficiency of diagnosing pediatric stroke.
Abstract

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