Related Experiment Video
Updated: May 13, 2026

Percutaneous Hepatic Perfusion PHP with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Hepatic failure with Providencia rettgeri infection: case report
Fangfei Yan1, Meiwen Han1, Qianting Guan1
1Department and Institute of Infectious Disease, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonostic Infectious Disease, Huazhong University.
Providencia rettgeri, an opportunistic pathogen, caused a rare lung infection in a critically ill patient with liver failure. This case highlights the challenges of treating antimicrobial-resistant infections in vulnerable patients.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Providencia rettgeri is an uncommon opportunistic pathogen frequently causing urinary tract and skin infections.
- Infections in patients with hepatic failure are rarely reported.
- Nosocomial infections pose significant challenges in intensive care settings.
Purpose of the Study:
- To report a rare case of Providencia rettgeri lung infection in a patient with severe hepatic failure.
- To highlight the association of this pathogen with critical illness and antimicrobial resistance.
- To emphasize the need for vigilance in managing such infections.
Main Methods:
- Case report of a 29-year-old male with a crushing injury leading to hepatic failure.
- Diagnosis of Providencia rettgeri pneumonia via fiber bronchoscopy and bronchoalveolar lavage fluid culture.
- Patient management in an infectious intensive care unit with mechanical ventilation.
Main Results:
- Providencia rettgeri was identified in the bronchoalveolar lavage fluid of a patient with severe liver failure and trauma.
- The patient experienced significant complications including postoperative issues and extensive burns.
- This highlights a rare instance of Providencia rettgeri pneumonia in a ventilated patient.
Conclusions:
- Providencia rettgeri poses a significant threat in critically ill patients, particularly those with compromised liver function.
- Antimicrobial resistance associated with Providencia rettgeri can lead to prolonged recovery and increased mortality.
- Close monitoring and prompt management are crucial for patients with this opportunistic infection.
Related Concept Videos
Diseases of the Liver and Gallbladder
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment
Hepatitis
Viral Hepatitis I: Introduction
Hepatic Encephalopathy

