Stenosis of Sigmoid Neovagina with Subsequent Pelvic Infection and Surgical Excision

Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome involves Müllerian abnormalities including agenesis of the upper vagina. Patients often elect for the creation of a neovagina, which can be performed via intestinal vaginoplasty to allow for penetrative sexual intercourse. We present a case of a 38-year-old female with MRKH who underwent sigmoid vaginoplasty and presented 12 years later with diffuse neovaginal closure, resulting in pelvic abscess formation and sepsis. She ultimately required surgical excision of the sigmoid neovagina for source control of the infection. This case highlights the importance of lifelong aftercare following vaginoplasty and incorporation of multidisciplinary teams in medically complex patients with complications from neovagina reconstruction.