Orthostatic hypotension in pancreatic cancer

Orthostatic hypotension is a relatively common medical diagnosis and can be debilitating for the patients it affects. There is a range of treatment options, though only one medication is licensed in the UK for treatment of orthostatic hypotension.We review the case of a man in his 70s with pancreatic cancer who developed orthostatic hypotension towards the latter stage of his disease that caused severe dizziness, impacting his quality of life. Multiple factors contributed to his orthostatic hypotension and various treatments, both non-pharmacological and pharmacological, were trialled, with varying degrees of success, to alleviate his symptoms and improve his quality of life. On reviewing his case, we identify that the medication options have different optimal scenarios in which they are effective.