Related Experiment Video

Updated: May 8, 2025

Photobleaching Assays FRAP & FLIP to Measure Chromatin Protein Dynamics in Living Embryonic Stem Cells
09:18

Photobleaching Assays FRAP & FLIP to Measure Chromatin Protein Dynamics in Living Embryonic Stem Cells

Published on: June 29, 2011

27.1K

Powerful protein editors offer new ways of probing living cells

Asher Mullard

    Nature
    |May 2, 2025
    PubMed
    Abstract

    No abstract available in PubMed .

    Keywords:
    BiochemistryCRISPR-Cas9 genome editingCell biology

    More Related Videos

    Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment
    09:02

    Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

    Published on: April 20, 2018

    19.6K
    Cell-Type Specific Protein Purification and Identification from Complex Tissues Using a Mutant Methionine tRNA Synthetase Mouse Line
    07:39

    Cell-Type Specific Protein Purification and Identification from Complex Tissues Using a Mutant Methionine tRNA Synthetase Mouse Line

    Published on: April 13, 2022

    2.7K

    Related Experiment Videos

    Last Updated: May 8, 2025

    Photobleaching Assays FRAP & FLIP to Measure Chromatin Protein Dynamics in Living Embryonic Stem Cells
    09:18

    Photobleaching Assays FRAP & FLIP to Measure Chromatin Protein Dynamics in Living Embryonic Stem Cells

    Published on: June 29, 2011

    27.1K
    Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment
    09:02

    Split-BioID — Proteomic Analysis of Context-specific Protein Complexes in Their Native Cellular Environment

    Published on: April 20, 2018

    19.6K
    Cell-Type Specific Protein Purification and Identification from Complex Tissues Using a Mutant Methionine tRNA Synthetase Mouse Line
    07:39

    Cell-Type Specific Protein Purification and Identification from Complex Tissues Using a Mutant Methionine tRNA Synthetase Mouse Line

    Published on: April 13, 2022

    2.7K

    Related Concept Videos

    Protein Dynamics in Living Cells01:19

    Protein Dynamics in Living Cells

    2.0K
    Different fluorescence-based techniques are used to study the protein dynamics in living cells. These techniques include FRAP, FRET, and PET.
    Fluorescent recovery after photobleaching (FRAP) is a fluorescent-protein-based detection technique used to quantify protein movement rates within the cell. This method exposes a small portion of the cell to an intense laser beam. The laser beam causes permanent photobleaching of the fluorophore-tagged proteins in the exposed region. As the bleached...
    2.0K

    Articles linked to this work by shared authors, journal, and citation graph.

    A thermodynamically favoured molecular computer.

    Nature·2026

    Molecular-level observation of the self-assembly of a virus-like particle.

    Nature·2026

    Heterogeneous photonic integration of single-crystalline nanomembranes.

    Nature·2026

    Assessing biological degradation of non-hydrolysable synthetic polymers.

    Nature·2026

    Electrically controllable superconducting memory effect in UTe2.

    Nature·2026

    Continuous-wave laser absorption spectroscopy of the thorium-229 nucleus.

    Nature·2026

    Differences of 3D and Mixed 2D and 3D Culture in the Generation of Human iPSC-Derived Hepatocytes.

    Biotechnology and bioengineering·2026

    Topologically complex knotted proteins are processed differentially by ATP-dependent proteases ClpXP and ClpAP.

    Protein science : a publication of the Protein Society·2026

    Post-translational protein S-palmitoylation in renal tubular injury: mechanisms and therapeutic implications.

    Frontiers in cell and developmental biology·2026

    Proximity labeling: A powerful tool for mapping protein interactions.

    Biosensors & bioelectronics·2026

    VPS13D protects against alcohol- associated steatohepatitis by regulating organelle contacts and VLDL secretion.

    Hepatology (Baltimore, Md.)·2026

    DisPhaseDB 2.0: Improved interpretation of disease-associated variants in liquid-liquid phase separation proteins with agent-accessible querying.

    Protein science : a publication of the Protein Society·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us