Hearts apart: exploring sex disparity in the global and regional burden of ischemic heart disease; a systematic analysis from the global burden of disease study 1990-2021
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View abstract on PubMed
Summary
This summary is machine-generated.The global burden of ischemic heart disease (IHD) shows narrowing gender gaps in prevalence and incidence, but declining sex parity in mortality and disability. Continued monitoring and sex-specific strategies are crucial for equitable IHD outcomes.
Area Of Science
- Cardiovascular Epidemiology
- Global Health
- Sex Differences in Disease
Background
- Ischemic heart disease (IHD) burden is historically lower in women, but this gap has narrowed.
- Understanding evolving gender disparities in IHD is critical for public health.
Purpose Of The Study
- To evaluate global trends and gender differences in ischemic heart disease (IHD) burden.
- Analyze demographic and regional variations in IHD from 1990 to 2021.
Main Methods
- Utilized Global Burden of Disease Study data (1990-2021).
- Estimated IHD burden using incidence, prevalence, mortality, YLLs, YLDs, and DALYs.
- Analyzed trends by age, sex, and sociodemographic index.
Main Results
- Global sex parity ratio (SPR) for IHD prevalence and incidence increased.
- SPR for age-standardized prevalence (ASPR) rose from 0.610 to 0.653.
- SPR for age-standardized incidence (ASIR) rose from 0.631 to 0.670.
- SPR for age-standardized mortality rate (ASMR) and DALY rates (ASDR) declined globally and in most regions.
Conclusions
- Progress in reducing IHD burden is evident.
- Increasing sex disparities in certain regions and age groups necessitate ongoing surveillance.
- Adaptive health policies and sex-specific healthcare are vital for equitable outcomes.
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