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Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
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Cardiac benign metastatic leiomyoma- a comprehensive review

Pankaj Garg1, Mostafa Ali1, Mohammad Alomari2

  • 1Department of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL, USA.

Cardio-Oncology (London, England)
|May 2, 2025
PubMed

Insights

Cardiac benign metastatic leiomyoma (BML) is a rare tumor often misdiagnosed, potentially causing severe heart issues. Early diagnosis and management are vital for preventing complications and improving patient outcomes.

Area of Science:

  • Cardiology
  • Oncology
  • Pathology

Background:

  • Cardiac benign metastatic leiomyoma (BML) is a rare cardiac tumor.
  • It is often asymptomatic and misdiagnosed, leading to serious complications like heart failure and death.
  • A history of uterine leiomyomas increases suspicion in women.

Purpose of the Study:

  • To review current knowledge on cardiac BML.
  • To highlight diagnostic challenges and emphasize thorough evaluation.
  • To discuss management strategies and improve clinical awareness.

Main Methods:

  • Literature review summarizing demographics, presentation, pathogenesis, diagnosis, and management.
  • Emphasis on clinical history, physical examination, and imaging studies.
  • Review of treatment options including surgical resection and castration.

Main Results:

  • Cardiac BML requires consideration in cardiac mass differential diagnosis.
  • Diagnostic challenges exist, necessitating comprehensive patient assessment.
  • Treatment options include surgery and hormonal therapies.

Conclusions:

  • Early diagnosis and prompt management of cardiac BML are critical.
  • Increased awareness among clinicians can improve patient care and outcomes.
  • This review offers insights for managing this rare condition.

Keywords:
Cardiac benign metastatic leiomyomaCardiac tumorsGenetic studiesSurgical treatment

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