Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

3.3K
Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SETD2 Deficiency Drives Mitochondrial DNA Leakage and Creates a Druggable Dependency on BCL-XL in Clear Cell Renal Cell Carcinoma.

Cancer research·2026
Same author

Lateral force microscopy calibration using an interferometric atomic force microscope.

The Review of scientific instruments·2026
Same author

Complex Deformation Characteristics of Liposomes during Atomic Force Microscopy Force Curves.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Association between depressive symptoms and tuberculosis diagnosis stage in older adults: a 4-year longitudinal cohort study in rural South Africa.

BMJ open·2025
Same author

Effects of pension eligibility expansion on men's memory decline and dementia probability: Findings from the HAALSI cohort in rural South Africa, 2014-2021.

PloS one·2025
Same author

Machine Learning-Based Reward-Driven Tuning of Scanning Probe Microscopy: Toward Fully Automated Microscopy.

ACS nano·2025
Same journal

Optimizing the Development Process in Direct Photolithography for Efficient PeLEDs.

Small methods·2026
Same journal

Fluorinated Diluents Enable Crowded Solvation Environments to Form Anion-Rich SEIs for High-Performance Potassium-Ion Batteries.

Small methods·2026
Same journal

Delocalized Redox Framework of Indanthrone Enables Low-Strain and Durable Mn<sup>2+</sup>/H<sup>+</sup> Storage in Aqueous Batteries.

Small methods·2026
Same journal

Sandgrouse Feather-Inspired Multiscale Hierarchical Microstructured Surfaces via IICSA for Controlled Liquid Regulation.

Small methods·2026
Same journal

Smart Antibacterial Janus Fabric Based on PVDF/Ag-Decorated-MXene for Unidirectional Water Transport and Thermal Management.

Small methods·2026
Same journal

Synergistic Anion Confinement in a Poly(Ionic Liquid)/MOF Composite Electrolyte Decouples Ionic Conductivity and Mechanical Strength for High-Performance Solid-State Lithium Metal Batteries.

Small methods·2026
See all related articles

Related Experiment Video

Updated: May 9, 2025

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays
05:04

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

1.4K

3D Vector Piezoresponse Imaging with Interferometric Atomic Force Microscopy.

Roger Proksch1, Ryan Wagner2

  • 1Asylum Research an Oxford Instruments Company, Santa Barbara, CA, 93117, USA.

Small Methods
|May 3, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces a new 3D interferometric method for Atomic Force Microscope (AFM) force measurements, simplifying complex workflows. The technique accurately quantifies tip-sample forces in three dimensions, particularly for piezoelectric materials.

Keywords:
Piezoresponseferroelectricvector PFM

More Related Videos

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping
14:13

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Published on: October 24, 2014

11.7K
Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid
10:25

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

16.6K

Related Experiment Videos

Last Updated: May 9, 2025

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays
05:04

Author Spotlight: Introduction to Active Probe Atomic Force Microscopy with Quattro-Parallel Cantilever Arrays

Published on: June 13, 2023

1.4K
Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping
14:13

Atomic Force Microscopy of Red-Light Photoreceptors Using PeakForce Quantitative Nanomechanical Property Mapping

Published on: October 24, 2014

11.7K
Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid
10:25

Sub-nanometer Resolution Imaging with Amplitude-modulation Atomic Force Microscopy in Liquid

Published on: December 20, 2016

16.6K

Area of Science:

  • Materials Science
  • Nanotechnology
  • Physics

Background:

  • Atomic Force Microscope (AFM) force measurements are typically limited to 1D or 2D.
  • Existing 3D AFM force measurement methods are complex and time-consuming.

Purpose of the Study:

  • To develop an accurate, simplified interferometric method for quantifying the full 3D response of an AFM tip to localized forces.
  • To enable quantitative 3D force measurements independent of sample orientation.

Main Methods:

  • Demonstration of an accurate, interferometric technique for 3D AFM force quantification.
  • Application of the method to piezoelectric materials for validation.

Main Results:

  • The interferometric method provides quantitative 3D force measurements with reduced noise and high accuracy.
  • Vertical piezo sensitivity (deff,z) was found to be systematically 2-3x larger than in-plane sensitivities (deff,lat).
  • Measured stiffness ratios align with theoretical predictions based on material moduli.

Conclusions:

  • The developed method simplifies angle-resolved piezoresponse force microscopy (PFM).
  • This approach offers a general framework for various AFM-based mechanical measurements beyond ferroelectric materials.