Constituents of Erysimum inconspicuum. Two sulfur-containing lactone compounds

The alcohol extract of Erysimum inconspicuum fruits, which exhibited cytotoxic activity against the KB cell line and some activity against the P-388 lymphocytic leukemia in vivo, was studied. Strophanthidin, uzarigenin, and two sulfur-containing lactones, erysulfone[6-methylsulfonyl-4-hydroxyhexanoic acid lactone] and erysulfoxide[6-methylsulfinyl-4-hydroxyhexanoic acid lactone], were isolated and characterized by spectral data.