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Related Concept Videos

Gallbladder01:17

Gallbladder

238
The gallbladder is a small, pear-shaped organ that plays a crucial role in our digestive system. Measuring about 10 cm in length, it is comparable in size to a kiwi fruit and is located in a hollow area on the lower surface of the liver. The gallbladder's primary function is to store and concentrate bile, a fluid produced by the liver that aids in digestion.
The gallbladder's anatomy consists of three regions: the fundus, body, and neck. Extending from the neck, the cystic duct joins...
238
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

334
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
334

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Measurement of abdominal fluid bilirubin concentration frequently fails to detect biliary tract rupture in dogs with gallbladder mucocele.

Journal of the American Veterinary Medical Association·2026
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Optimization and validation of a TaqMan real-time PCR for the detection of Heterobilharzia americana in dog feces.

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Diagnosis and management of gallbladder mucocele formation in dogs.

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Auranofin is lethal against feline Tritrichomonas foetus in vitro but ineffective in cats with naturally occurring infection.

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Acquired dysfunction of CFTR underlies cystic fibrosis-like disease of the canine gallbladder.

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Increased lipogenesis and lipidosis of gallbladder epithelium in dogs with gallbladder mucocele formation.

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Related Experiment Video

Updated: May 9, 2025

Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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Gallbladder Mucocele.

Jody L Gookin1

  • 1Small Animal Internal Medicine, Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC 27607, USA.

The Veterinary Clinics of North America. Small Animal Practice
|May 3, 2025
PubMed
Summary
This summary is machine-generated.

Gallbladder mucocele in dogs is a growing concern, often deadly and poorly understood. Recent studies are improving diagnosis and treatment, with ongoing research into its underlying causes.

Keywords:
BiliaryCanineCholecystectomyCholestasisMucus

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Area of Science:

  • Veterinary Medicine
  • Canine Pathology

Background:

  • Gallbladder mucocele (GBM) is an increasingly prevalent and severe condition in dogs.
  • Historically rare, GBM is now a common cause of gallbladder disease with high mortality.
  • Understanding GBM pathogenesis is crucial for improving canine health outcomes.

Purpose of the Study:

  • To review current knowledge on gallbladder mucocele in dogs.
  • To highlight advancements in diagnosis, treatment, and prognosis.
  • To identify gaps in understanding GBM pathogenesis.

Main Methods:

  • Retrospective analysis of multiple large canine patient studies.
  • Review of existing literature on GBM diagnosis and treatment.
  • Exploration of emerging research into GBM formation mechanisms.

Main Results:

  • Numerous studies provide data on GBM diagnosis, concurrent diseases, surgical outcomes, and prognosis.
  • Surgical intervention remains a primary treatment modality for GBM.
  • Pathogenesis research is limited but beginning to elucidate underlying mechanisms.

Conclusions:

  • Gallbladder mucocele is a significant and often fatal canine disease.
  • Improved diagnostic and therapeutic strategies are informed by extensive research.
  • Further investigation into GBM pathogenesis is essential for future prevention and treatment.