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  1. Home
  3. Long-term Exposure To Residential Greenness And Cardiovascular Disease And All-cause Mortality In China.
  1. Home
  3. Long-term Exposure To Residential Greenness And Cardiovascular Disease And All-cause Mortality In China.

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Long-term exposure to residential greenness and cardiovascular disease and all-cause mortality in China.

Xue Cao1, Nuerguli Tuerdi1, Haosu Tang2,3

  • 1Division of Prevention and Community Health, National Center for Cardiovascular Disease, National Clinical Research Center of Cardiovascular Disease, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing, 102308, China.

BMC Public Health
|May 3, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

Higher residential greenness is linked to lower cardiovascular disease (CVD) risk in China. Modifiable factors like cholesterol and physical activity partially explain this protective effect, supporting green space in public health strategies.

Keywords:
Cardiovascular diseaseEpidemiologyGreennessMediation analysis

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Area of Science:

  • Environmental Health
  • Cardiovascular Epidemiology
  • Public Health

Background:

  • Limited evidence exists on residential greenness and cardiovascular disease (CVD) risk in developing nations like China.
  • This study addresses the gap by examining the association between residential greenness and CVD outcomes in a large Chinese cohort.

Purpose of the Study:

  • To evaluate the association of residential greenness with CVD incidence and all-cause mortality.
  • To explore the mediating roles of modifiable risk factors in the greenness-CVD association.

Main Methods:

  • A cohort of 22,702 adults aged 35+ was followed from 2012-2019.
  • Residential greenness was quantified using Normalized Difference Vegetation Index (NDVI) at multiple buffer sizes (300m, 500m, 1000m).
  • Multivariable Cox regression and causal mediation analysis were used to assess associations and mediation effects.

Main Results:

  • Higher residential greenness (NDVI) was significantly associated with reduced CVD risk (e.g., HR per tertile increment for NDVI500m: 0.86).
  • Living in areas with high NDVI500m showed a 26% lower CVD incidence compared to the lowest NDVI500m areas (HR: 0.74).
  • Key mediators included high-density lipoprotein cholesterol (16.18%), physical activity (5.34%), body mass index (4.04%), and diabetes (2.45%).

Conclusions:

  • Increased residential greenness is associated with a lower risk of cardiovascular disease in the adult Chinese population.
  • Specific modifiable risk factors partially mediate the protective effect of greenness on CVD.
  • Findings highlight the importance of integrating green space initiatives into public health strategies for CVD prevention.