2025 American Association for Thoracic Surgery (AATS) Expert Consensus Document: Surgical management of acute

David J Kaczorowski1, Koji Takeda2, Pavan Atluri3

  • 1Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pa.

Insights

Managing complications of acute myocardial infarction (AMI) is crucial. This expert consensus report focuses on mechanical circulatory support and other strategies to improve outcomes for AMI patients facing serious complications.

Area of Science:

  • Cardiology
  • Cardiothoracic Surgery
  • Critical Care Medicine

Background:

  • Complications following acute myocardial infarction (AMI) contribute significantly to patient morbidity and mortality.
  • Effective management strategies are essential for improving outcomes in these complex cases.

Purpose of the Study:

  • To provide evidence-based recommendations for managing patients with acute myocardial infarction (AMI) complications.
  • To emphasize the role of mechanical circulatory support (MCS) in treating severe AMI complications.

Main Methods:

  • A multidisciplinary expert committee, including cardiologists and cardiothoracic surgeons, was convened.
  • Systematic literature review and expert consensus using the Delphi process were employed to develop recommendations.

Main Results:

  • Clinical recommendations were formulated based on synthesized literature review results and expert clinical experience.
  • Guidance covers general considerations, revascularization, cardiogenic shock, mechanical complications (e.g., rupture), arrhythmias, and durable therapies.

Conclusions:

  • Acute myocardial infarction (AMI) can lead to life-threatening cardiogenic shock, arrhythmias, and mechanical failures.
  • Prompt intervention, including the judicious use of mechanical circulatory support, is vital for managing these high-mortality complications.
Abstract

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Acute Coronary Syndrome V: Nursing Management01:26

Acute Coronary Syndrome V: Nursing Management

Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...