Related Experiment Video
Updated: May 9, 2025

Author Spotlight: Regenerative Peripheral Nerve Interface (RPNI) Surgery in Postamputation Pain Management
Published on: March 15, 2024
Benefits of an Enhanced Recovery Pathway for Lower Extremity Amputation Patients
Angela D Sickels1, Clara Hua1, Kory Dees1
1Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.
Enhanced recovery programs (ERPs) reduce complications and readmissions for lower extremity amputation (LEA) patients. ERPs also expedite prosthetic device receipt, improving survival rates through early ambulation.
Area of Science:
- Surgical outcomes research
- Patient recovery protocols
- Amputation care management
Background:
- Enhanced Recovery Programs (ERPs) utilize interdisciplinary collaboration, patient education, multimodal pain control, and early mobilization.
- ERPs show potential to improve care for patients undergoing lower extremity amputation (LEA).
Purpose of the Study:
- To evaluate the impact of ERPs on outcomes for patients undergoing major LEA.
- To compare outcomes between patients receiving ERP care and a historical pre-ERP cohort.
Main Methods:
- Retrospective cohort study comparing ERP patients (02/2022-07/2023) with a pre-ERP cohort (01/2020-01/2022).
- Analysis of length of stay (LOS), perioperative complications, time to prosthetic receipt, and achieved K-level ambulation.
- Subgroup analysis for staged procedures, below-knee amputation (BKA), and above-knee amputation (AKA).
Main Results:
- ERP patients experienced fewer 30-day readmissions and 90-day complications, particularly those undergoing staged procedures.
- ERP below-knee amputation (BKA) patients showed reduced 90-day mortality (2.5% vs. 12.2%).
- ERP above-knee amputation (AKA) patients had a shorter LOS (6 vs. 7 days), and the overall ERP cohort had faster prosthetic receipt (176 vs. 226 days).
Conclusions:
- ERP implementation is associated with improved outcomes, including reduced complications and readmissions for LEA patients.
- Faster prosthetic receipt in ERP patients is crucial, given the link between ambulation and improved survival.
- The significant comorbidities in LEA patients underscore the value of ERP-centered optimization strategies.
More Related Videos
05:07Author Spotlight: Implementing the Enhanced Recovery After Surgery Concept in Rehabilitation Following Anterior Cruciate Ligament Reconstruction
Published on: March 1, 2024
00:09Synergizing Antegrade Endoscopic with Bridging Vein Harvesting for Improvement of Great Saphenous Vein Graft Quality from the Lower Leg
Published on: November 19, 2019