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Accelerometer-derived "weekend warrior" and regularly active physical activity and incident diabetes.
Lubi Lei1, Jingkuo Li1, Wei Wang2
1National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Obesity (Silver Spring, Md.)
|May 5, 2025
Summary
Engaging in moderate-to-vigorous physical activity (MVPA), even as a weekend warrior (WW), significantly lowers diabetes risk. Both WW and regularly active (RA) patterns offer similar protection compared to being inactive.
Area of Science:
- Public Health
- Epidemiology
- Exercise Science
Background:
- Diabetes mellitus is a major global health concern.
- Understanding the impact of physical activity patterns on diabetes risk is crucial for prevention strategies.
- Previous research has primarily focused on total weekly physical activity, with less attention to how activity is distributed throughout the week.
Purpose of the Study:
- To investigate the association between different patterns of moderate-to-vigorous physical activity (MVPA) and the risk of developing diabetes.
- To compare the diabetes risk reduction associated with the "weekend warrior" (WW) physical activity pattern versus regularly active (RA) and inactive patterns.
Main Methods:
- A prospective cohort study involving 85,934 participants from the UK Biobank.
- Participants were categorized into "weekend warrior" (WW), "regularly active" (RA), and "inactive" based on MVPA levels (≥150 min/week or ≥230.4 min/week) and distribution (≥50% of MVPA in 1-2 days for WW).
- Cox proportional hazards regression models were used to analyze the associations between MVPA patterns and incident diabetes.
Main Results:
- The "weekend warrior" (WW) physical activity pattern was associated with a reduced risk of diabetes (HR: 0.76, 95% CI: 0.69-0.84) compared to being inactive.
- The "regularly active" (RA) pattern also showed a significant reduction in diabetes risk (HR: 0.64, 95% CI: 0.56-0.73).
- These findings were consistent when using both the guideline-based and sample median thresholds for MVPA.
Conclusions:
- The "weekend warrior" physical activity pattern confers a similar protective effect against diabetes as the "regularly active" pattern.
- Achieving recommended levels of moderate-to-vigorous physical activity, even when concentrated into fewer days, is effective in lowering diabetes risk.
- These results highlight the importance of physical activity volume, regardless of its distribution, for diabetes prevention.
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