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Persistent facial erythema in an infant

Sarah Lee1,2, Fiona Lynch1,2, Pierre-Olivier Grenier1,2

  • 1Harvard Medical School, Boston, Massachusetts.

JAAD Case Reports
|May 5, 2025
PubMed
Summary

No abstract available in PubMed .

Keywords:
infantlupusneonatal lupus erythematosuspediatric dermatology

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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