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Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
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Suicide Reattempt Risk Factors: A Cross-Sectional Study Using Mashhad's Population-Based Registry, 2019-2022.

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  • 1Department of Epidemiology, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran.

Iranian Journal of Public Health
|May 5, 2025
PubMed
Summary
This summary is machine-generated.

Substance use significantly increases the likelihood of suicide reattempts by 43%. Identifying drug abuse is crucial for targeted interventions and suicide prevention strategies in high-risk populations.

Keywords:
IranPoisson multivariateRisk factorsSuicideSuicide reattempt

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Area of Science:

  • Public Health
  • Epidemiology
  • Mental Health Research

Background:

  • Suicide is a major global health concern, ranking as the fourth leading cause of death for young adults aged 15-29.
  • Understanding factors contributing to suicide reattempts is vital for developing effective prevention strategies.

Purpose of the Study:

  • To investigate the key factors associated with suicide reattempts.
  • To identify demographic and clinical characteristics that predict repeat suicide attempts.

Main Methods:

  • A cross-sectional study utilizing electronic health records from Mashhad, Iran (2019-2022).
  • Data included 5,737 individuals with documented suicide attempts.
  • Poisson multivariable regression analysis was employed to determine predictors of reattempt frequency.

Main Results:

  • The overall suicide reattempt rate was 10.1%, with higher prevalence among men, individuals with mental disorders, substance users, single individuals, those with high school education, and self-employed persons.
  • Substance users exhibited a 43% increased likelihood of suicide reattempt (IRR=1.43, p<0.001) after adjusting for other variables.

Conclusions:

  • Substance abuse is a significant risk factor for suicide reattempts.
  • Identifying individuals with substance use disorders is critical for targeted interventions to prevent suicide reattempts and reduce mortality.