Long-term results of palliative placement of very low-axial force self-expandable metallic stents for malignant colorectal obstruction
- Rika Kyo 1, Takashi Sasaki 2, Shuntaro Yoshida 3, Hiroyuki Isayama 4, Tomonori Yamada 5, Toshiyuki Enomoto 6, Yorinobu Sumida 7, Toshio Kuwai 8, Masafumi Tomita 9, Takeaki Matsuzawa 10, Rintaro Moroi 11, Toshiyasu Shiratori 12, Yoshihisa Saida 6
- Rika Kyo 1, Takashi Sasaki 2, Shuntaro Yoshida 3
- 1Department of Gastroenterology Saiseikai Yokohamashi-Nanbu Hospital Kanagawa Japan.
- 2Department of Hepato-Biliary-Pancreatic Medicine Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
- 3Department of Endoscopy and Endoscopic Surgery Graduate School of Medicine The University of Tokyo Tokyo Japan.
- 4Department of Gastroenterology Graduate School of Medicine Juntendo University Tokyo Japan.
- 5Department of Gastroenterology Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital Aichi Japan.
- 6Department of Surgery Toho University Ohashi Medical Center Tokyo Japan.
- 7Department of Gastroenterology National Hospital Organization Kyushu Medical Center and Clinical Research Center Fukuoka Japan.
- 8Department of Gastroenterology National Hospital Organization Kure Medical Center and Chugoku Cancer Center Hiroshima Japan.
- 9Department of Surgery Kobe Ekisaikai Hospital Hyogo Japan.
- 10Department of Surgery Imusumiyoshi General Hospital Saitama Japan.
- 11Division of Gastroenterology Tohoku University Hospital Miyagi Japan.
- 12Department of Gastroenterology Kameda Medical Center Chiba Japan.
- 0Department of Gastroenterology Saiseikai Yokohamashi-Nanbu Hospital Kanagawa Japan.
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View abstract on PubMed
Summary
This summary is machine-generated.This study found that very low axial force (AF) stents are safe and effective for palliative colorectal stent placement. These stents demonstrated low rates of adverse events like perforation, migration, and occlusion, supporting their use in malignant obstruction.
Area Of Science
- Gastroenterology
- Oncology
- Medical Devices
Background
- Malignant colorectal obstruction often requires palliative stent placement.
- High axial force (AF) stents are linked to increased perforation risk.
- Evaluating low AF stents is crucial for improving patient safety and outcomes.
Purpose Of The Study
- To assess the long-term safety and efficacy of a very low axial force (AF) stent for palliative colorectal decompression.
- To determine the rates of adverse events, survival, and patency associated with these stents.
Main Methods
- Eighty-one patients with malignant colorectal obstruction received a very low AF stent.
- Adverse events (perforation, migration, occlusion), 1-year survival, and cumulative patency were evaluated.
- Statistical analyses included Fisher's exact test and Kaplan-Meier survival analysis.
Main Results
- The 1-year cumulative survival rate was 37.8%.
- Cumulative patency rates at 1 year were 75.8%.
- Adverse events were low: migration (6.2%), occlusion (9.9%), and perforation (2.5%).
Conclusions
- Very low axial force (AF) stents are safe and effective for palliative management of malignant colorectal obstruction.
- These stents represent a suitable option for improving patient outcomes in this setting.
- No perforations occurred in patients receiving bevacizumab post-stenting.
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