Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Physical Methods for Controlling Microbial Growth: Temperature

Physical Methods for Controlling Microbial Growth: Temperature

Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Inertial sensing of water content in tumor spheroids.

Science advances·2026

Same author

In Situ Monitoring of Diffusive Morphology Transformation of Semiconductor Materials under Joule Heating.

ACS applied materials & interfaces·2026

Same author

Inertial sensing of water content in tumor spheroids.

bioRxiv : the preprint server for biology·2025

Same author

Advanced operation of heated fluidic resonators via mechanical and thermal loss reduction in vacuum.

Microsystems & nanoengineering·2023

Same author

Massively parallel electro-optic sampling of space-encoded optical pulses for ultrafast multi-dimensional imaging.

Light, science & applications·2023

Same author

Nanomechanical Sensing Using Heater-Integrated Fluidic Resonators.

Nano letters·2022

Same journal

Parallelized contactless microfluidic dispenser with superhydrophobic nozzles for scalable combinatorial screening.

Biomicrofluidics·2026

Same journal

Time resolved luminescence of millisecond lifetime dyes in droplet microfluidic systems.

Biomicrofluidics·2026

Same journal

Emerging trends in functional molecularly imprinted polymers for electrochemical detection of biomarkers.

Biomicrofluidics·2025

Same journal

Deep learning assisted mechanotyping of individual cells through repeated deformations and relaxations in undulating channels.

Biomicrofluidics·2025

Same journal

<i>Giardia</i> purification from fecal samples using rigid spiral inertial microfluidics.

Biomicrofluidics·2025

Same journal

Point of care sepsis diagnosis: Exploring microfluidic techniques for sample preparation, biomarker isolation, and detection.

Biomicrofluidics·2025

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 14, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

Advanced microfluidic systems with temperature modulation for biological applications.

J Ko¹, J Lee¹

¹Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon-si, South Korea.

Biomicrofluidics

|May 5, 2025

Summary

This summary is machine-generated.

Microfluidic platforms with precise thermal control enable rapid biological applications like nucleic acid amplification and cancer therapy. Integrating advanced sensing enhances single-cell analysis and diagnostics for precision medicine.

More Related Videos

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Published on: November 26, 2019

Related Experiment Videos

Last Updated: Jun 14, 2026

Thermal Measurement Techniques in Analytical Microfluidic Devices

Thermal Measurement Techniques in Analytical Microfluidic Devices

Published on: June 3, 2015

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression

Published on: October 6, 2019

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Controlling Flow Speeds of Microtubule-Based 3D Active Fluids Using Temperature

Published on: November 26, 2019

Area of Science:

Biomedical Engineering
Microfluidics
Thermal Engineering

Background:

Precise temperature control is crucial for microfluidic applications in biology.
Lab-on-a-chip systems require advanced thermal modulation for various functions.

Purpose of the Study:

To provide a comprehensive review of state-of-the-art microfluidic platforms utilizing thermal modulation.
To highlight advanced multi-modal sensing methods integrated within microfluidics.
To discuss future challenges and opportunities in microfluidic thermal management.

Main Methods:

Review of microfluidic platforms with nanoparticle-driven induction, photothermal, and electrothermal heating.
Discussion of integrated sensors, quantum-based techniques (nanodiamond NV centers), and suspended microchannel resonators.
Analysis of thermal modulation strategies for applications like nucleic acid amplification, hyperthermia, and cell lysis.

Main Results:

Microfluidic thermal modulation platforms support diverse applications including rapid nucleic acid amplification, cancer hyperthermia, and cellular lysis.
Integration of advanced multi-modal sensing, including quantum-based methods, expands microfluidic capabilities.
Enhanced sensing enables single-cell analysis, metabolic profiling, and scalable diagnostics.

Conclusions:

Microfluidic thermal modulation coupled with advanced sensing drives innovation in biomedical applications.
Addressing system integration, scalability, and cost-effectiveness is key for future development.
These advancements promise breakthroughs in precision medicine and high-throughput biomedical research.