Pathological predictors for curettage and cementation outcome in proximal tibial giant cell tumors

Proximal tibia giant cell tumors (GCT) are aggressive with high-recurrence rate, function-affecting and benign neoplasms. Therefore, it is of interest to report the pathological predictors for curettage and cementation outcome in proximal tibial giant cell tumors. Hence, 32 patients treated with curettage, poly-methyl-methacrylate (PMMA) cementation and locking plate fixation between 2018 and 2022 was included in this study. The average age of patients was 28.1 ± 6.9 years and most tumors were Grade 2 (campanacci grade) with 62.5% cortical involvement. The average musculo-skeletal tumor society (MSTS) score was 27.2 ± 4.2 with acceptable function. Thus, tumor grade and cortical involvement were the main predictors of recurrence, reflecting the need for targeted treatment.