Related Experiment Video
Updated: May 9, 2025
Oral Biofilm Formation on Different Materials for Dental Implants
Published on: June 24, 2018
Osseo-integration potential of zirconia versus titanium implants
Pratesh Dholabhai1, Surabhi Thakur2, Deepak Sharma3
1Department of Oral and Maxillofacial Surgery, K.M Shah Dental College and Hospital, Sumandeep Vidyapeeth Deemed to be University, Gujarat, India.
Abstract:
The success of dental implants depends on osseo-integration because titanium (Ti) maintains good mechanical stability while zirconia (Zr) prevents bacterial adhesion. The early-stage adhesion of MG-63 osteo-blast-like cells to Ti surfaces reached 78% ± 2.5% during the initial period (p<0.05). However, Zr demonstrated superior long-term cell proliferation and mineralization throughout the analysis period (p<0.05). The alkaline phosphatase (ALP) levels at day 7 remained comparable between Ti (1.25 ± 0.09 U/mL) and Zr (1.18 ± 0.07 U/mL) while Zr showed better growth of mineralized surface at day 14. Nonetheless, additional testing using animal subjects are required to confirm Zr as a suitable substitute for Ti implants.
