Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

301
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
301
Cancer Therapies02:49

Cancer Therapies

7.4K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.4K
Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

5.4K
Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...
5.4K
Clinical Trials: Overview01:11

Clinical Trials: Overview

2.5K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
2.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barriers to patient engagement with community-based resources following social determinants of health (SDOH) screening: a mixed-methods study across hospitals in the Chicago metropolitan area.

BMJ public health·2026
Same author

Characterizing Alcohol Use and Expectancies for Alcohol Analgesia Among Breast Cancer Survivors With Arthralgia.

Psycho-oncology·2026
Same author

Health behaviors among young adult cancer survivors and the importance of task self-efficacy.

Journal of cancer survivorship : research and practice·2026
Same author

Higher intensity care for patients with multiple chronic conditions after hospital-physician integration.

Health affairs scholar·2026
Same author

Effect of a Symptom Surveillance and Collaborative Care Intervention on Palliative Care Utilization.

Journal of pain and symptom management·2026
Same author

Psychometric properties of the Clinical Sustainability Assessment Tool (CSAT) short form across three research centers evaluating effectiveness and implementation of a cancer symptom surveillance and management intervention.

Implementation science communications·2026
Same journal

Error in Grant Number in Funding/Support Section.

JAMA network open·2026
Same journal

The Supplementary Role of Friends in Caregiving Networks.

JAMA network open·2026
Same journal

Urbanicity, Neighborhood Conditions, and Dementia Mortality.

JAMA network open·2026
Same journal

Equity and Cancer Survival Among Veterans Health Administration Patients: A Systematic Review and Meta-Analysis.

JAMA network open·2026
Same journal

Limbic System Microstructure in Neonates With Antenatal Opioid Exposure.

JAMA network open·2026
Same journal

Risk and Protective Factors for Suicide Mortality in Youths: A Systematic Review and Meta-Analysis.

JAMA network open·2026
See all related articles

Related Experiment Video

Updated: May 12, 2025

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.2K

Web-Based Cancer Symptom Self-Management System: A Randomized Clinical Trial.

David Cella1, Nicola Lancki2, Maja Kuharic1

  • 1Department of Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

JAMA Network Open
|May 5, 2025
PubMed
Summary
This summary is machine-generated.

Adding a bilingual web-based self-management program to electronic health record (EHR)-integrated patient-reported outcomes (cPRO) did not reduce symptom burden or healthcare resource use (HCRU) in cancer patients. Low engagement suggests a need for improved intervention strategies.

More Related Videos

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.2K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

179

Related Experiment Videos

Last Updated: May 12, 2025

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
06:28

E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

Published on: August 1, 2019

8.2K
Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
07:13

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform

Published on: April 12, 2021

4.2K
Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery
06:46

Competing-Risk Nomogram for Predicting Cancer-Specific Survival in Multiple Primary Colorectal Cancer Patients after Surgery

Published on: September 27, 2024

179

Area of Science:

  • Oncology
  • Digital Health
  • Health Services Research

Background:

  • Cancer patients and survivors often experience significant symptom burden, impacting quality of life and increasing healthcare utilization.
  • Effective symptom management is crucial for patient-centered cancer care.

Purpose of the Study:

  • To assess if a bilingual (English/Spanish) web-based self-management program, added to electronic health record (EHR)-integrated patient-reported outcome (cPRO) assessment, can reduce symptom burden and healthcare resource use (HCRU) in cancer patients.
  • To evaluate the effectiveness of enhanced care (EC) versus usual care (UC) in managing cancer symptoms and resource utilization.

Main Methods:

  • A patient-level randomized clinical trial involving 1614 adult cancer patients and survivors across 30 clinics.
  • Participants received either usual care (UC) with EHR-integrated cPRO or enhanced care (EC) with an added web-based self-management program.
  • Outcomes included Patient-Reported Outcomes Measurement Information System measures (anxiety, depression, fatigue, pain, physical function) and HCRU (inpatient visits, ED visits, hospital days) over 12 months.

Main Results:

  • No statistically significant differences were observed between the enhanced care (EC) and usual care (UC) groups for any cPRO outcomes over 12 months.
  • Healthcare resource utilization (HCRU) also showed no significant differences between the EC and UC groups.
  • Website engagement was low, with only 52.1% accessing the program and 47% of those returning, spending a median of 45 seconds per visit.

Conclusions:

  • The addition of a bilingual web-based self-management program to EHR-integrated cPRO did not significantly reduce symptom burden or HCRU in this patient population.
  • Low engagement with the web-based intervention highlights a critical need for developing strategies to improve participation and tailor digital health tools for maximum benefit.
  • Further research is needed to optimize digital interventions for cancer symptom management and reduce healthcare resource use.