Related Experiment Video
Updated: May 9, 2025
12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
18.5K
Type 1 diabetes mellitus in children: Patient reported outcomes
Basima A Almomani1, Roa'a N Elayyan1, Samah F Al-Shatnawi1
1Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.
Plos One
|May 5, 2025
Summary
This study found that pediatric patients with type 1 diabetes mellitus (T1DM) in Jordan showed above-average insulin adherence and quality of life (QoL), despite widespread poor glycemic control. Interventions are recommended to improve adherence and patient outcomes.
Area of Science:
- Pediatric Endocrinology
- Diabetes Mellitus Research
- Patient-Reported Outcomes
Background:
- Increasing global prevalence of type 1 diabetes mellitus (T1DM) in children and adolescents.
- Poor glycemic control in pediatric T1DM leads to significant health issues, reduced quality of life (QoL), and increased healthcare utilization.
- Understanding patient-reported outcomes is crucial for managing T1DM in pediatric populations.
Purpose of the Study:
- To assess self-management adherence, QoL, diabetes-related stigma, and glycemic control in insulin-treated pediatric T1DM patients in Jordan.
- To identify determinants influencing these patient-reported outcomes and clinical indicators.
- To provide insights for targeted interventions to improve T1DM management in Jordanian youth.
Main Methods:
- A cross-sectional study involving 150 pediatric T1DM patients in Northern Jordan (April-October 2023).
- Face-to-face interviews using validated, Arabic-translated tools for adherence (Diabetes Management Questionnaire), QoL (Pediatric Quality of Life Inventory 3.0 Diabetes Module), and stigma (Child Attitude Toward Illness Scale).
- Glycemic control assessed via glycated hemoglobin (HbA1c) levels.
Main Results:
- Mean adherence score was 57.4 ± 18.13; younger age, higher income, and shorter disease duration were linked to better adherence.
- Mean QoL score was 63.27 ± 11.86; male gender and absence of disease-related factors correlated with lower QoL.
- 76% of patients had uncontrolled diabetes; disease duration and maternal education influenced glycemic control. BMI and family history of DM were linked to stigma.
Conclusions:
- Despite challenges, pediatric T1DM patients in Jordan demonstrate favorable insulin adherence and QoL.
- Significant proportion of patients exhibit uncontrolled diabetes, highlighting the need for improved management strategies.
- Targeted interventions focusing on adherence determinants and glycemic control are recommended to enhance overall patient outcomes.
Related Concept Videos
01:22Diabetes Mellitus: Overview and Type I Subtype
2.3K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.3K
01:22Diabetes Mellitus: Type 2 and Gestational
2.1K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.1K
01:16Insulin: Dosing Regimen and Adverse Effects
121
Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
121
01:15Diabetes: Symptoms, Diagnosis, and Complications
471
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
471
01:20Pathophysiology of Diabetes
805
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
805
01:15Diabetes: Management and Pharmacotherapy
204
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
204