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Published on: March 26, 2018
The American Association for Thoracic Surgery (AATS) 2025 Expert Consensus Document: Surgical management of mitral
Ahmed E El-Eshmawi1, Monika Halas2, Brian T Bethea3
1Department of Cardiovascular Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
Insights
Managing mitral annular calcification (MAC) surgery is complex. This expert consensus provides 33 recommendations for patient selection, surgical, and transcatheter interventions for MAC, improving treatment strategies.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Cardiac Imaging
Background:
- Mitral annular calcification (MAC) presents significant challenges in mitral valve disease management.
- High perioperative morbidity and mortality rates underscore the need for standardized approaches.
- Increasing prevalence of MAC necessitates updated clinical guidelines.
Purpose of the Study:
- To provide a simplified management outline for MAC.
- To guide patient selection, imaging, and therapeutic options (surgical and transcatheter).
- To focus on conventional surgical techniques and hybrid approaches for MAC.
Main Methods:
- An international expert panel of cardiac surgeons and interventionalists was assembled.
- A comprehensive literature review was conducted.
- Clinical recommendations were developed using a modified Delphi method.
Main Results:
- Consensus was achieved on 33 recommendations.
- Recommendations cover preoperative evaluation, patient selection, surgical techniques, hybrid procedures, and transcatheter interventions for MAC.
- Guidance is provided on managing complications and bailout strategies for MAC interventions.
Conclusions:
- Consensus was reached on key recommendations for managing complex MAC patients.
- The guidelines offer practical support for clinicians treating MAC.
- These recommendations aim to improve outcomes for patients with MAC undergoing interventions.
Objective:
Surgery for mitral valve disease in patients with mitral annular calcification (MAC) remains challenging. There is no consensus on the ideal management strategy or patient selection, and perioperative and periprocedural morbidity and mortality rates remain high. The recent surge of patients presenting with MAC has been accompanied by increased interest in MAC surgery and interventions. This expert consensus document is meant to provide a simplified outline for managing MAC, including patient selection, imaging, and surgical and transcatheter therapeutic options, with a particular focus on conventional surgical techniques and hybrid approaches.
Methods:
The American Association for Thoracic Surgery Clinical Practice Standards Committee assembled an international panel of cardiac surgeons and structural heart interventionalists with established expertise in the field of MAC. A comprehensive literature review was performed by the panel and a medical librarian. Clinical recommendations were developed utilizing a modified Delphi method.
Results:
Expert consensus was reached on 33 recommendations, with class of recommendation and level of evidence, for each of 5 main topics: (1) preoperative evaluation for patients with MAC, patient selection, and indications for intervention; (2) standard surgical techniques in MAC; (3) hybrid procedures in MAC; (4) transcatheter MAC interventions; and (5) complications and bailout of MAC surgery and interventions.
Conclusions:
Despite the complexity and heterogenicity of patients presenting with MAC, consensus on several key recommendations was reached by this American Association for Thoracic Surgery expert panel. These recommendations provide guidance for cardiac surgeons and structural heart interventionists in treating most patients who present with MAC.
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