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Related Experiment Video

Updated: May 16, 2025

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis

Published on: April 10, 2019

Necrotising enterocolitis in adults: a rare occurrence.

Summi Karn¹, Karamveer Singh², Krishna Rajakumar¹

¹Department of General Surgery, All India Institute of Medical Sciences, Rishikesh, Rishikesh, Uttarakhand, India.

BMJ Case Reports

|May 5, 2025

Summary

Adult necrotising enterocolitis (ANEC) is rare but life-threatening. This case report highlights diagnostic challenges and emphasizes the need for early diagnosis and management of ANEC in adults, differentiating it from the neonatal form.

Keywords:

Gastroenterology Gastrointestinal surgery

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Last Updated: May 16, 2025

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Published on: April 10, 2019

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Published on: June 8, 2022

Author Spotlight: Enhancing Understanding and Treatment Strategies with the NEC-on-a-Chip Model

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Published on: July 28, 2023

Area of Science:

Gastroenterology
Critical Care Medicine
Surgical Pathology

Background:

Necrotising enterocolitis (NEC) is a severe intestinal condition primarily affecting preterm infants.
Adult NEC (ANEC) is a rare and often undiagnosed condition with significant mortality.
Timely diagnosis and intervention are critical for improving outcomes in ANEC.

Purpose of the Study:

To report a case of ANEC in an elderly patient.
To emphasize the diagnostic challenges associated with ANEC.
To highlight key differences between neonatal NEC and ANEC.

Main Methods:

Case report of an octogenarian patient presenting with acute abdomen.
Clinical and radiological evaluation for acute abdominal conditions.
Surgical and pathological confirmation of ANEC.

Main Results:

The patient was diagnosed with ANEC, a rare condition in adults.
The case illustrated significant diagnostic difficulties.
Key distinctions between neonatal NEC and ANEC were identified.

Conclusions:

ANEC is a rare but critical diagnosis in adults presenting with acute abdomen.
Early recognition and prompt management are essential for reducing mortality in ANEC.
Further research is needed to understand and manage ANEC effectively.