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How much can biomarkers explain sociodemographic inequalities in cognitive dysfunction and cognitive impairment?

Eric T Klopack1, Mateo P Farina2, Bharat Thyagarajan3

  • 1Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.

Journal of Alzheimer'S Disease : JAD
|May 6, 2025
PubMed

Keywords:
Alzheimer’s diseasebiomarkersmachine learningmultiomicssociodemographic factors

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Intelligence is often thought to be linked to brain size, but the relationship is more complex than that. While brain size does correlate modestly with some abilities, like verbal skills, the connection is weaker for others, such as spatial reasoning. Other factors, like brain structure, also play crucial roles. For instance, despite Einstein's smaller-than-average brain, his parietal cortex, which is involved in spatial reasoning, was 15% wider, suggesting that neural density might matter...
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