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Single Central Suture Mueller Muscle Conjunctival Resection Without Phenylephrine Test: 6-Year Experience
Pelin Celiker1, Diane Wang2,3, Wenyu Deng2
1Tschannen Eye Institute, University of California, Davis, Sacramento, California.
Ophthalmic Plastic and Reconstructive Surgery
|May 6, 2025
Summary
This study shows that a revised single central suture Mueller muscle conjunctival resection (csMMCR) effectively treats involutional ptosis without a preoperative phenylephrine test (PPT), achieving good eyelid symmetry and minimal reoperations.
Area of Science:
- Ophthalmology
- Oculoplastics
- Surgical Techniques
Background:
- Involutional ptosis is commonly managed with Mueller muscle conjunctival resection (MMCR).
- The preoperative phenylephrine test (PPT) traditionally guides MMCR decisions.
- Various MMCR techniques exist, necessitating outcome evaluation.
Purpose of the Study:
- To evaluate the efficacy of a revised single central suture MMCR (csMMCR) for involutional ptosis, specifically without the use of PPT.
- To assess outcomes including margin reflex distance-1 (MRD1), eyelid symmetry, and complication rates.
Main Methods:
- Retrospective review of 597 patients (985 eyelids) undergoing csMMCR without PPT by a single surgeon.
- Exclusion criteria included other ptosis etiologies, short follow-up, prior eyelid surgery, poor levator function, or significant dry eye.
- Outcomes measured were MRD1 at 3 months postoperatively, symmetry, complications, and reoperation rates.
Main Results:
- A mean MRD1 increase of 2.72 mm was observed at 3 months postoperatively.
- 95.1% of patients achieved eyelid symmetry within 1 mm (p < 0.001).
- The reoperation rate for residual ptosis was 1.42%, with no reported complications.
Conclusions:
- The revised single central suture Mueller muscle conjunctival resection (csMMCR) is an effective surgical option for involutional ptosis.
- This technique can be successfully performed without the need for a preoperative phenylephrine test (PPT) in select patients.
- csMMCR offers good functional and aesthetic outcomes with a low reoperation rate for suitable candidates.

