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Immunoproteomic Response to IL-17A Blockade in a Patient With Generalized Pustular Psoriasis: New Insights From

Yu-Chen Jeng1, Yi-Chen Liao1, Yi-Kai Hong1,2

  • 1Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

The Journal of Dermatology
|May 6, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
IL‐17IL‐6generalized pustular psoriasisixekizumabproteomics

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
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