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Updated: May 9, 2025

Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3
Published on: April 7, 2023
Treatment of eosinophilic annular erythema with upadacitinib
Wanyan Xiang1, Siqi Zhang1, Qiuju Li2
1Department of Dermatology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Introduction:
Eosinophilic ring erythema (EAE) is a rare eosinophilic dermatosis characterized by ring-shaped or arc-shaped papules and plaques, with eosinophilic infiltration throughout the dermis. Due to the rarity of EAE, established treatment guidelines are currently lacking.
Case Report:
In this report, we present a case of a middle-aged male patient with EAE who exhibited a poor response to systemic immunosuppressants but responded favorably to upadacitinib.
Conclusion:
This case highlights the potential utility of upadacitinib in managing EAE, particularly in patients unresponsive to conventional therapies.
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