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Blind Procedures

Blind Procedures

Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which child was...

Blinding

Blinding

Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.

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Related Experiment Video

Updated: May 19, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Published on: January 11, 2019

Prospective, Randomized, Intra-subject Controlled Trial Comparing Ultrasound-guided Thread and Mini-open Carpal

Joshua J Meaike¹, Ike B Hasley², Jeffrey S Brault²

¹Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.

Journal of Surgical Orthopaedic Advances

|May 6, 2025

Summary

This summary is machine-generated.

Ultrasound-guided, incisionless thread carpal tunnel release (TCTR) is as effective and safe as mini-open carpal tunnel release (MOR) for carpal tunnel syndrome. Most patients preferred TCTR due to faster recovery and less pain.

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Published on: May 26, 2023

Metacarpal Small Incision for Carpal Tunnel Syndrome

Metacarpal Small Incision for Carpal Tunnel Syndrome

Published on: April 5, 2024

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Last Updated: May 19, 2026

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies

Published on: January 11, 2019

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Metacarpal Small Incision for Carpal Tunnel Syndrome

Metacarpal Small Incision for Carpal Tunnel Syndrome

Published on: April 5, 2024

Area of Science:

Orthopaedic Surgery
Minimally Invasive Procedures
Musculoskeletal Disorders

Background:

Carpal tunnel syndrome (CTS) is a common condition causing hand numbness and weakness.
Traditional treatments include conservative management and surgical release.
Mini-open carpal tunnel release (MOR) is a standard surgical approach.

Purpose of the Study:

To compare the efficacy and safety of ultrasound-guided, incisionless thread carpal tunnel release (TCTR) versus MOR.
To evaluate functional outcomes, pain, and strength after bilateral carpal tunnel release.

Main Methods:

Prospective, single-institution, randomized, intrasubject controlled study.
Bilateral carpal tunnel syndrome patients underwent same-day TCTR and MOR.
Eleven patients were followed for 12 months post-surgery.

Main Results:

No significant clinical or statistical differences in functional outcomes, pain, or strength between TCTR and MOR.
All but one patient preferred TCTR over MOR.
Patients cited quicker recovery and decreased pain with TCTR.

Conclusions:

Ultrasound-guided TCTR is a safe and effective alternative to MOR for carpal tunnel syndrome.
TCTR offers comparable functional outcomes with potential advantages in patient recovery and comfort.
This minimally invasive technique shows promise for carpal tunnel syndrome treatment.