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Updated: May 9, 2025

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Microfluidic Tools for Probing Fungal-Microbial Interactions at the Cellular Level
Published on: June 23, 2022
3.4K
Plant-microbe interactions: A transcriptional switch governing fungal lifestyle shifts
Alga Zuccaro1, Antonio Di Pietro2
1Institute for Plant Sciences, University of Cologne, Cluster of Excellence on Plant Sciences (CEPLAS), 50674 Cologne, Germany.
Current Biology : CB
|May 6, 2025
Abstract:
Fungi interact with plants in ways that can be beneficial or detrimental. A new study demonstrates that upregulating a single transcription factor in a beneficial fungal endophyte is sufficient to convert it into a pathogen.
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Transcription
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Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
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Riboswitches are non-coding mRNA domains that regulate the transcription and translation of downstream genes without the help of proteins. Riboswitches bind directly to a metabolite and can form unique stem-loop or hairpin structures in response to the amount of the metabolite present. They have two distinct regions – a metabolite-binding aptamer and an expression platform.
The aptamer has high specificity for a particular metabolite which allows riboswitches to specifically regulate...
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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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