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Updated: Jul 18, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
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Published on: February 28, 2012

Atrial Fibrillation in a Patient with Hemophilia A: A Case Report and Therapeutic Challenges

Karina Althaus1,2, Jürgen Schreieck3, Günalp Uzun1,2

  • 1Center for Clinical Transfusion Medicine, University Hospital of Tübingen, Tübingen, Germany.

Hamostaseologie
|May 6, 2025
PubMed

The increasing age of patients with congenital hemophilia poses new challenges for clinicians. Not only the consequences of bleeding but also age-related diseases, especially cardiovascular disorders, are of great concern. Factors such as hypertension, diabetes, or hyperlipidemia further increase the cardiovascular risk in elderly patients with hemophilia. Preventive treatment of these cardiovascular diseases may therefore also be necessary in hemophilia patients. However, determining the optimal level of anticoagulation in patients with reduced levels of coagulation factors is often difficult and requires an individualized approach. Given the absence of substantial evidence from large clinical trials, clinicians rely on case reports and expert opinions to guide the therapy. This case report details the individual risk-benefit assessment and management of a 57-year-old hemophilia A patient with atrial fibrillation.

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