Different clinical presentations of persistent placoid maculopathy: a case series

Area of Science:

• Ophthalmology
• Retinal Diseases
• Chorioretinopathy

Background:

• Persistent placoid maculopathy is a rare idiopathic bilateral chorioretinopathy.
• This condition is characterized by distinct ocular manifestations.

Purpose of the Study:

• To report diverse clinical presentations of persistent placoid maculopathy.
• To expand understanding of the ocular manifestations of this rare condition.

Main Methods:

• Retrospective case series analysis of four patients with persistent placoid maculopathy.
• Utilized ophthalmological examinations, multimodal imaging, and patient history.
• Included cases with associated giant cell arteritis and post-transplant immunosuppression.

Main Results:

• Case 1: Giant cell arteritis presentation with macular atrophy despite corticosteroids.
• Case 2: Developed type 2 choroidal neovascularization, improved with anti-VEGF therapy.
• Case 3: Submacular hemorrhage and subsequent choroidal neovascularization.
• Case 4: Vision recovery with corticosteroids during immunosuppressive therapy.

Conclusions:

• Persistent placoid maculopathy exhibits a wide spectrum of clinical presentations.
• Management strategies vary based on individual patient factors and complications.
• This series broadens the understanding of this rare chorioretinopathy.