Related Experiment Video
Updated: May 12, 2025

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound 30/45MHZ System
Published on: May 5, 2018
Heart Diseases in Pregnancy: A Comprehensive Analysis of Maternal and Neonatal Outcomes
Ruchi Bansal1, Nitesh Goyal2, Chandrashekhar Shrivastava1
1Obstetrics and Gynaecology, All India Institute of Medical Sciences, Raipur, IND.
Abstract:
Objective This study aims to evaluate the prevalence, maternal and neonatal outcomes, and clinical implications of heart diseases in pregnancy. Methods A prospective observational study was conducted on pregnant women diagnosed with heart disease. Maternal and neonatal outcomes, including mortality, preterm birth, and mode of delivery, were assessed. Statistical comparisons were made based on ejection fraction (EF < 30% vs. EF ≥ 30%). Results Peripartum cardiomyopathy (n = 10, 27.78%) and rheumatic heart disease (n = 10, 27.78%) were the most prevalent cardiac conditions, followed by prosthetic valve disease and acyanotic congenital heart disease, each contributing to 11.11% (n = 4) of cases. A significant proportion of patients (n = 20, 55.56%) presented between 32 and 37 weeks of gestation. The study observed a maternal mortality rate of 13.89% (n = 5), with a stark contrast between women with an EF of <30% (n = 4, 33.33% mortality) and those with an EF of ≥30% (n = 1, 4.17% mortality). ICU admissions were required in 22.22% (n = 8) of cases, predominantly in women with an EF of <30% (n = 6, 50% vs. n = 2, 8.33%). Vaginal delivery was achieved in 66.67% (n = 24) of cases, while 27.78% (n = 10) underwent cesarean section. Among neonatal outcomes, 77.78% (n = 28) of infants were preterm, 52.78% (n = 19) had low birth weight (LBW), and 30.56% (n = 11) were small for gestational age (SGA). NICU admissions were recorded in 19.44% (n = 7) of cases, with a neonatal mortality rate of 5.56% (n = 2). Conclusion Heart diseases in pregnancy significantly impact both maternal and neonatal outcomes. Early detection and multidisciplinary management are crucial for improving prognosis and reducing complications.
Related Concept Videos
Fetal Circulation
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Adrenergic Antagonists: ɑ and β-Receptor Blockers
Teratogenicity
Hormonal Regulation
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...
Cardiovascular Drugs: Classification based on Therapeutic Indications

