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Comparing functional outcomes of glansectomy with or without glans reconstruction
Mihály Murányi1, András Domoszlai1, Attila Csaba Nagy2
1Department of Urology, University of Debrecen, Debrecen, 4032, Hungary.
The Canadian Journal of Urology
|May 7, 2025
Summary
Glansectomy with reconstruction (GR) offers excellent functional outcomes for penile cancer patients, significantly improving erectile and cosmetic results compared to penile amputation (PA). Glansectomy alone (GA) showed no significant functional advantage over PA.
Area of Science:
- Urology
- Oncology
- Reconstructive Surgery
Background:
- Penile cancer and intraepithelial neoplasia require surgical intervention.
- Comparing different surgical techniques is crucial for optimizing patient outcomes.
Purpose of the Study:
- To compare oncological and functional outcomes of glansectomy with reconstruction (GR) versus glansectomy alone (GA) and penile amputation (PA).
Main Methods:
- Retrospective study of patients diagnosed between 2017-2022.
- Surgical, oncological, and functional outcomes were assessed via chart review and patient questionnaires.
- Patients were grouped into GR (A), GA (B), and PA (C).
Main Results:
- GR group had 0% complication rate, 17% margin positivity, and 0% local recurrence.
- PA group had 29% complication rate and 14% local recurrence.
- GR significantly predicted better erectile function and cosmetic outcomes compared to PA, but not GA.
Conclusions:
- Glansectomy with reconstruction yields excellent functional results.
- The functional benefits of GR are most significant when compared to penile amputation.

