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Updated: Jun 15, 2026
Color Spot Test As a Presumptive Tool for the Rapid Detection of Synthetic Cathinones
Published on: February 5, 2018
Identification and Structural Elucidation of a Novel Pyrrolidinophenone-Based Designer Drug on the Illicit Market:
Sara Casati1,2, Roberta F Bergamaschi1, Riccardo Primavera3
1Dipartimento di Scienze Biomediche, Chirurgiche ed Odontoiatriche, Università degli Studi di Milano, 20133 Milan, Italy.
Abstract:
The identification of a new psychoactive substances (NPS) with a cathinone structure and a biphenyl substituent, found in seized powder from the black market, is here reported. By combining analytical techniques, including 1D and 2D NMR and HRMS, the compound was identified as 1-([1,1'-biphenyl]-4-yl)-2-(pyrrolidin-1-yl)pentan-1-one (α-BPVP), an α-pyrrolidinopentiophenone (α-PVP) analogue featuring a biphenyl group instead of the phenyl ring. This previously unreported molecule raises urgent legal and public health concerns, which warrants further toxicological investigation.
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