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Cyanoacrylate Adhesive With Titanium Plate Fixation for Deep Brain Stimulation Leads: A Case Series and Technical
Pablo Ramon Fruett da Costa1, Guilherme Oliveira de Paula2, Helen Michaela de Oliveira2
1Department of Functional Neurosurgery, Sinedor Clinic, Sinop , Mato Grosso , Brazil.
Operative Neurosurgery (Hagerstown, Md.)
|May 7, 2025
Summary
A novel deep brain stimulation (DBS) lead fixation technique using n-butyl-2-cyanoacrylate and a titanium plate offers improved aesthetics and function. This method avoids complications like cranial deformities and electrode migration, enhancing patient satisfaction.
Area of Science:
- Neurosurgery
- Biomaterials Science
Background:
- Deep brain stimulation (DBS) is crucial for Parkinson disease, but conventional lead fixation causes complications like cranial deformities and migration.
- Current methods often compromise both cosmetic and functional outcomes.
Purpose of the Study:
- To introduce and evaluate a novel DBS lead fixation technique using n-butyl-2-cyanoacrylate adhesive and a titanium "dog-bone" plate.
- To improve esthetic results and reduce complications associated with DBS lead placement.
Main Methods:
- Retrospective analysis of 32 patients with Parkinson disease undergoing DBS with the novel fixation technique.
- Application of n-butyl-2-cyanoacrylate at the burr-hole site, followed by titanium plate stabilization.
- Monitoring for lead migration, infection, and patient satisfaction for up to 21.6 months.
Main Results:
- Successful lead fixation in all patients, with no migration, displacement, or mechanical failure.
- No postoperative infections, seizures, or meningitis reported, indicating a favorable safety profile.
- High patient satisfaction due to smooth cranial contour and reduced operative time.
Conclusions:
- The n-butyl-2-cyanoacrylate and titanium plate technique is an effective, aesthetically superior, and cost-efficient alternative for DBS lead fixation.
- This method demonstrates reduced complication rates and enhanced patient satisfaction, suggesting its potential as a future standard.
- Further multicenter studies are recommended to validate these findings.
