Related Experiment Video
Updated: May 8, 2025

Brain Imaging Investigation of the Neural Correlates of Emotion Regulation
Published on: August 26, 2011
Cross-Species Framework for Emotional Well-Being and Brain Aging: Lessons From Behavioral Neuroscience
F Vankee Lin1, Janine M Simmons2, Adam Turnbull1
1Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California.
Importance:
Emotional well-being (EWB) is an emerging therapeutic target for managing and preventing symptoms associated with Alzheimer disease and related dementias (ADRD). However, more research is needed to establish causal inferences between brain changes, EWB, and behavioral changes observed in typical aging and ADRD.
Observations:
This article presents a framework for using a cross-species behavioral neuroscience approach to study EWB and brain aging, adopting a well-established biobehavioral model that highlights the reciprocal roles of brain changes, EWB, and ADRD symptoms. First, the challenges and opportunities in this field are reviewed. Then, a practical solution to improve comparability between animal and human studies is proposed.
Conclusions And Relevance:
The goal is to draw comprehensive parallels and distinctions that could enhance the understanding of the mechanisms linking brain aging, EWB, and ADRD symptomatic disturbances across different species.
More Related Videos
05:59Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
Published on: October 6, 2023
10:13Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
Published on: February 14, 2014
Related Concept Videos
Functional Brain Systems: Limbic System
Empathy
Introduction to Biological Bases of Psychology
The nervous system, the cornerstone of...
The Sympathetic Nervous System
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Physiology of Emotion
Autonomic Nervous System
The autonomic nervous system (ANS) plays a critical role in emotional responses by regulating involuntary physiological functions. It consists of two main components: the sympathetic and parasympathetic systems. The sympathetic system...