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Updated: May 12, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Bidirectional relationships between mindfulness and symptoms of depression and anxiety during pregnancy and
Izaskun Orue1, Oiana Echabe-Ecenarro1,2
1Department of Psychology, Faculty of Health Sciences, University of Deusto, Bilbao, Spain.
Background:
Perinatal anxiety and depression are significant public health concerns with the potential to affect maternal and infant well-being; therefore, it is crucial to identify protective factors. This study explores the reciprocal relationship between dispositional mindfulness and symptoms of anxiety and depression throughout pregnancy and the postpartum period.
Methods:
In a sample of 347 women, mindfulness traits were evaluated at 26 weeks of gestation and two weeks postpartum, while anxiety and depression symptoms were evaluated at 26 weeks of gestation and at two and six weeks postpartum.
Results:
The results indicate that higher levels of non-judging mindfulness during pregnancy predicted reduced depression symptoms at two weeks postpartum, and similarly, higher levels of non-judging mindfulness at two weeks postpartum predicted lessened depression symptoms at six weeks postpartum. Moreover, depressive symptoms during pregnancy predicted reduced mindfulness capacities (non-judging of and non-reactivity to inner experience) in the postpartum period.
Conclusion:
These findings underscore the importance of promoting mindfulness during pregnancy as a means to prevent and manage postpartum mood disorders, highlighting the dynamic interplay between mental health symptoms and mindfulness traits.
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