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Updated: May 14, 2025

Generation and Multi-phenotypic High-content Screening of Coxiella burnetii Transposon Mutants
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Host Genetic Factors in Q Fever Susceptibility

José-María Robaina Bordón1,2, José-Luis Pérez-Arellano3, Olga Montes-Ares4

  • 1Department of Clinical and Surgical Sciences, University of Las Palmas de Gran Canaria [ULPGC], 35001 Las Palmas de Gran Canaria, Spain.

Pathogens (Basel, Switzerland)
|May 7, 2025
PubMed
Summary

Genetic factors influence susceptibility to Coxiella burnetii infection. While Toll-like receptor (TLR) gene variations showed no link, specific Human Leukocyte Antigen (HLA)-DRB1 variants were more common in acute Q fever patients.

Keywords:
Coxiella burnetiiQ feverhost genetic factors

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