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Hand hygiene01:23

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
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Surface Membrane Barriers01:18

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The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
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Updated: May 12, 2025

A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
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Facing Foodborne Pathogen Biofilms with Green Antimicrobial Agents: One Health Approach.

Ana Karina Kao Godinez1, Claudia Villicaña2, José Basilio Heredia1

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Summary

Unconventional antimicrobials like phages and plant extracts offer sustainable solutions to combat resilient bacterial biofilms in food environments. This approach enhances food safety and public health by reducing reliance on traditional antibiotics.

Keywords:
bacteriophagesbiofilmsessential oilsfoodborne pathogensgreen antimicrobials

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Area of Science:

  • Food Science
  • Microbiology
  • Public Health

Background:

  • Bacterial biofilms pose a significant threat to food safety and public health due to their persistence and resistance to conventional antimicrobials.
  • Controlling these biofilms is challenging, necessitating the exploration of alternative eradication strategies.

Purpose of the Study:

  • To review the application of unconventional antimicrobial agents for controlling foodborne pathogen biofilms.
  • To highlight the mechanisms of action, antibiofilm activities, and challenges of these agents.

Main Methods:

  • Literature review focusing on unconventional antimicrobials (bacteriophages, plant extracts, etc.) and their efficacy against foodborne biofilms.
  • Analysis of studies employing a "One Health" perspective for integrated food safety strategies.

Main Results:

  • Unconventional agents demonstrate novel mechanisms for targeting and disrupting biofilms.
  • These agents offer sustainable and effective alternatives to conventional antimicrobials, aiding in resistance management.

Conclusions:

  • Unconventional antimicrobials are promising for enhancing food safety and public health.
  • An integrated "One Health" approach is crucial for sustainable biofilm control and mitigating antimicrobial resistance in food systems.