Promoting large multinational academic clinical trials for gastrointestinal cancers in Europe: the ENGIC (European Network for GI Cancers) initiative
- J Taieb 1, J Seligmann 2, D Modest 3, C Girault 1, F Rivera 4, E Mahillo 4, P Osterlund 5, P Pfeiffer 5, D Malka 6, C Louvet 6, A R Siebenhuner 7, C Morf 7, C de la Fouchardiere 8, L Monard 8, M Koopman 9, G Vink 9, I Borbath 10, L Dewever 10, R Adams 2, A Reinacher-Schick 3, F Pietrantonio 10, S Lonardi 11, T Aparicio 1, C Cremolini 11,
- J Taieb 1, J Seligmann 2, D Modest 3
- 1Féderation Francophone de Cancérologie Digestive (FFCD), Dijon Cedex, France.
- 2British Colon Oncology Group (BCOG), Leeds University Clinical Trials Research Unit, Leeds, UK.
- 3Arbeitsgemeinschaft Internistische Onkologie (AIO), Berlin, Germany.
- 4Grupo de Tratamiento de los Tumores Digestivos (TTD), Madrid, Spain.
- 5Nordic Gastrointestinal Tumour Adjuvant Therapy Group (NORDIC), Tampere and University Hospitals, Tampere, Finland.
- 6Groupe Cooperateur Multidisciplinaire en Oncolgie (GERCOR), Paris, France.
- 7Swiss Colon Cancer Group (SAKK), Kompetenzzentrum, Bern, Switzerland.
- 8UNICANCER GI (UCGI), Paris, France.
- 9Dutch Colorectal Cancer Group (DCCTG), Nijmegen, The Netherlands.
- 10Belgian Group of Digestive Oncology (BGDO), Zaventem, Belgium.
- 11Gruppo Oncologico del Nord Ovest (GONO), Genova, Italy.
- 0Féderation Francophone de Cancérologie Digestive (FFCD), Dijon Cedex, France.
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View abstract on PubMed
Summary
This summary is machine-generated.This paper proposes the European Network for Gastro-Intestinal Cancers (ENGIC) to advance academic clinical trials for gastrointestinal cancers in Europe. The ENGIC model offers a framework for collaborative research in other disease areas.
Area Of Science
- Oncology
- Clinical Research
- Health Policy
Background
- Gastrointestinal cancers represent a significant health burden in Europe.
- There is a need for enhanced strategic collaboration in academic clinical trials for these cancers.
- Existing research networks may lack specific focus on gastrointestinal malignancies.
Purpose Of The Study
- To propose the establishment of a European Network for Gastro-Intestinal Cancers (ENGIC).
- To outline the structure, objectives, and operational framework for ENGIC.
- To present ENGIC as a potential model for other disease-specific research networks.
Main Methods
- The paper outlines a proposed organizational structure for ENGIC.
- Key components discussed include network objectives, governance, and operational activities.
- Future priority actions are identified to guide the network's development.
Main Results
- A detailed proposal for the setup of the ENGIC initiative is presented.
- The proposed structure encompasses presentation, objectives, organization, processes, activities, and governance.
- Priority actions for future development are delineated.
Conclusions
- The establishment of ENGIC is proposed to foster strategic academic clinical trials for gastrointestinal cancers in Europe.
- The proposed network structure and operational model are detailed.
- The ENGIC framework is suggested as a transferable model for other disease areas.
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