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Kimura disease: A rare case affecting the inguinal lymph node.

Nur Syafawani1, Ab Razak Samsudin1

  • 1Division of General Surgery, Department of Surgery, Faculty of Medicine, KPJU, Malaysia.

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|May 7, 2025
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Summary

Kimura disease (KD) is a rare inflammatory condition. This case highlights KD presenting as an inguinal mass in an elderly woman, successfully treated with surgery and corticosteroids.

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Area of Science:

  • Rare inflammatory disorders
  • Dermatology
  • Oncology

Background:

  • Kimura disease (KD) is a benign, chronic inflammatory disorder.
  • Typically presents as unilateral subcutaneous masses in the head and neck.
  • Etiology is uncertain, possibly immune-mediated.

Observation:

  • A 70-year-old woman presented with a painless, slow-growing inguinal mass.
  • Initial evaluations suggested a benign lesion, but malignancy could not be excluded.
  • Antibiotics provided temporary relief, but the swelling recurred.

Findings:

  • Histopathological examination confirmed Kimura disease with eosinophilic infiltration and lymphoid proliferation.
  • Elevated serum IgE levels were noted.
  • Surgical excision followed by corticosteroid therapy led to recovery.

Implications:

  • This case emphasizes the importance of considering Kimura disease in atypical locations like the inguinal region.
  • Awareness of rare presentations is crucial to avoid misdiagnosis and unnecessary interventions.
  • Effective management involves surgical excision and corticosteroid therapy.