Related Experiment Video
Updated: May 12, 2025

Contact-Free Co-Culture Model for the Study of Innate Immune Cell Activation During Respiratory Virus Infection
Published on: February 28, 2021
Dynamics of COVID-19 based on spontaneous individual behaviors of vaccination
Yunsu Zhou1, Xianning Liu1, Yangjiang Wei2
1Key Laboratory of Eco-environments in Three Gorges Reservoir Region (Ministry of Education), School of Mathematics and Statistics, Southwest University, Chongqing 400715, China.
Abstract:
As the COVID-19 vaccine becomes widely available, human self-protection awareness is gradually weakening. However, the epidemic still continue to erupt repeatedly in various areas. Therefore, it is necessary to reveal the relationship between vaccination and individual spontaneous behaviors and their impact on the epidemic. Based on an SVEIR epidemic dynamical model, a novel imitation dynamics model is established by integrating the dynamic changes of individual spontaneous behaviors before and after vaccination. Unvaccinated people are more likely to choose long-term individual spontaneous behavior change strategies to reduce the risk of infection. While the vaccinated individuals are more likely to choose multiple, short-term strategies of individual spontaneous behavior changes. In the case of low vaccine protective efficacy, the changes of individual spontaneous behavior will drive several small-scale outbreaks at the same time. Besides, when the value of R0 is 4.5 and vaccination rate is 0.45, keeping the vaccine protection efficacy above 76.3% can not only complement the epidemic recurrence caused by behavioral changes, but also effectively reduce the epidemic peak and therefore quickly control the epidemic. Our results reveal the underlying mechanisms between vaccination, vaccine protection efficacy, individual spontaneous behaviors of the two groups of people and the COVID-19 epidemic. Vaccination and its protective efficacy effectively have a reciprocal effect with individual behavior changes, so as to control the epidemic quickly and effectively.
Related Concept Videos
Vaccinations
Causality in Epidemiology
Principles of Disease Surveillance
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Single Nucleotide Polymorphisms-SNPs
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...

